Avalglucosidase Alfa-ngpt (By injection)
Avalglucosidase Alfa-ngpt (ay-val-gloo-KOE-si-dase AL-fa - ngpt)
Treats Pompe disease.
NexviazymeThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to avalglucosidase alfa-ngpt.
How to Use This Medicine:
- Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. It must be given slowly, so the needle will have to remain in place for 4 to 7 hours.
- A nurse or other health provider will give you this medicine.
- Your doctor will give you other medicines (including allergy, fever, or steroid medicine) before you receive this medicine to help prevent unwanted effects.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant or breastfeeding, or if you have heart disease or lung disease.
- This medicine may cause infusion-related reactions, which can be life-threatening and require medical attention.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blurred vision, headache, pounding in the ears, slow or fast heartbeat
- Chest pain, trouble breathing, cold sweats, blue lips, fingernails, or skin
- Fever, chills, cough, sore throat, body aches
- Lightheadedness, dizziness, fainting
- Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
- Swelling in your hands, ankles, or feet
If you notice these less serious side effects, talk with your doctor:
- Constipation, diarrhea, nausea, vomiting, stomach pain
- Muscle or joint pain
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 6/2/2022
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