Selexipag (By injection)
Treats pulmonary arterial hypertension (PAH).
UptraviThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to selexipag.
How to Use This Medicine:
- Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. It must be given slowly, so the needle will have to remain in place for at least 80 minutes.
- A nurse or other health provider will give you this medicine.
- Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Do not use this medicine together with gemfibrozil.
- Some medicines can affect how selexipag works. Tell your doctor if you are also using clopidogrel, deferasirox, rifampin, or teriflunomide.
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease or other lung or breathing problems.
- This medicine may cause pulmonary edema (fluid in the lungs), especially in patients with pulmonary venoocclusive disease.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blue lips and fingernails, cough, chest pain, swelling in the legs or ankles
- Lightheadedness or fainting
If you notice these less serious side effects, talk with your doctor:
- Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 6/2/2022
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