Thiethylperazine (By injection)
Treats or prevents nausea and vomiting.
There may be other brand names for this medicine.
When This Medicine Should Not Be Used:
You should not use this medicine if you have ever had an allergic reaction to thiethylperazine or to related drugs such as Compazine®, Mellaril®, Thorazine®, or Trilafon®.
How to Use This Medicine:
- Your doctor will prescribe your exact dose and tell you how often it should be given.
- An IM injection is a shot given in your muscle (upper arm, thigh, buttocks).
- This medicine should be given by a nurse or other caregiver trained to give IV or IM medicine. Sometimes a family member or friend can be taught to give you this medicine.
- You should not use the medicine if it looks cloudy or has turned from clear to colored liquid.
If a dose is missed:
- This medicine needs to be given on a regular schedule. If you miss a dose, call your doctor for instructions.
How to Store and Dispose of This Medicine:
- Store this medicine in its original container. Keep at room temperature, away from heat and light. Do not freeze.
- Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are taking other medicines that may make you sleepy such as cold or allergy medicines, sleeping pills, tranquilizers, or narcotic pain killers.
- Avoid drinking alcohol while you are using thiethylperazine.
Warnings While Using This Medicine:
- If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
- Check with your doctor before using this medicine if you have a bone marrow disorder, liver problems, low or high blood pressure, circulation problems, or a seizure disorder (epilepsy).
- This medicine may make your skin more sensitive to sunlight. Use a sunscreen when outdoors. Avoid sunlamps or tanning beds.
- This medicine may make you very drowsy. Avoid driving a car or using machinery.
- Do not suddenly stop taking this medicine without asking your doctor. You may need to use smaller and smaller doses before stopping completely.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Skin rash, itching, or hives
- Trouble breathing
- Fast or irregular heartbeat
- Unexplained high fever, muscle stiffness
- Uncontrollable movements of the face, neck, or tongue
- Yellowing of eyes or skin
If you notice these less serious side effects, talk with your doctor:
- Dizziness, weakness, or headache
- Dry mouth, nose, and throat
- Constipation, stomach upset
- Muscle or skin discomfort where the shot is given
- Breast swelling, discharge, or tenderness
- Trouble urinating
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 8/5/2022
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